2-[6,8-Dibromo-3-(4-hydroxycyclohexyl)-1,2,3,4-tetrahydroquinazolin-2-yl]-6-methoxyphenol
نویسندگان
چکیده
The title compound, C(21)H(24)Br(2)N(2)O(3), was synthesized by the condensation reaction of 3-methoxy-salicylaldehyde with 4-(2-amino-3,5-dibromo-benzyl-amino)cyclo-hexa-nol in a methanol solution. The dihedral angle between the two benzene rings is 76.4 (3)°. The cyclo-hexyl ring adopts a chair configuration. There is an intra-molecular O-H⋯N hydrogen bond which affects the solid state conformation of the mol-ecule. The crystal structure is stabilized by inter-molecular O-H⋯O hydrogen bonds, forming chains running along the b axis.
منابع مشابه
2-[6,8-Dibromo-3-(4-hydroxycyclohexyl)-1,2,3,4-tetrahydroquinazolin-2-yl]phenol methanol 0.25-solvate
The title compound, C(20)H(22)Br(2)N(2)O(2)·0.25CH(4)O, was synthesized by the condensation reaction of salicyl-aldehyde with 4-(2-amino-3,5-dibromo-benzyl-amino)-cyclo-hexa-nol in methanol. There are four independent main mol-ecules and two half-occupied methanol solvent mol-ecules in the asymmetric unit. The dihedral angles between the two benzene rings in the four mol-ecules are 87.8 (6), 86...
متن کامل4-[6,8-Dibromo-2-(2-chloro-5-nitrophenyl)-1,2,3,4-tetrahydroquinazolin-3-yl]cyclohexanol
The title compound, C(20)H(20)Br(2)ClN(3)O(3), was synthesized by the condensation reaction of 2-chloro-5-nitro-benzaldehyde with 4-(2-amino-3,5-dibromo-benzyl-amino)cyclo-hexa-nol in a methanol solution. There are two independent mol-ecules in the asymmetric unit and in one mol-ecule the atoms of the cyclo-hexane ring are disordered over two sets of sites with refined occupancies of 0.657 (12)...
متن کامل3-(Prop-2-en-1-yl)-2-sulfanylidene-1,2,3,4-tetrahydroquinazolin-4-one
The tetra-hydro-quinazoline fused-ring system of the title compound, C(11)H(10)N(2)OS, is approximately planar (r.m.s. deviation = 0.019 Å). In the crystal, adjacent mol-ecules are linked by N-H⋯O hydrogen bonds, forming a chain running along the b axis.
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